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Glutathione-S-transferase (GSTP) that participates in the conjugation of GSH to reactive cysteines (S-glutathionylation) seems to play an important role in idiopathic pulmonary fibrosis lung fibrogenesis, since GSTP immunoreactivity is increased in the lungs of idiopathic pulmonary fibrosis patients, notably within type II epithelial cells (128, 129)

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Healthy skin always starts with a healthy liver

For example, TFEB-K91la impedes the ubiquitination and degradation of TFEB by weakening its interaction with the E3 ubiquitin ligase WWP2, ultimately leading to increased TFEB activity and autophagy flux in pancreatic cancer cells

Conversely, WT-Bcr-Abl cells after treatment with N-Acetyl-Cysteine (NAC), a GSH precursor that increased the cellular GSH level, exhibited not only increased lengths of replication tracks but also insensitive to JMF4073 (Fig

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